Bronze Sponsor
Nagase
No Booth
Tokyo 103-8355 JP
Phone: +81336653333 Fax: +81336653940 https://www.nagase.co.jp/pharma/english/
Company Profile

Oligonucleotide therapeutic represent a new and rapid growing class of biotherapeutics spinning a wide range of application such as antisense oligonucleotide (ASO), siRNA, RNA/DNA aptamer, and miRNA. Oligonucleotide substances are manufacturing by solid-phase synthetic method using phosphoramidite monomer on automated synthesizers. The conventional method is highly efficient, however, remaining significant problems for quality and price of synthesized oligonucleotide product. We developed novel nucleotide blockers and monomers as new building blocks for manufacturing of oligonucleotide substance. Presented here is its preparation process and applying to oligonucleotide synthesis in liquid and solid phase in use of our building blocks.

 In addition to this, we developed a novel microfluidic manufacturing platform for Liposome and LNP formulation, and are offering to serve as a CMO from lab scale (mL) to commercial GMP production (dozens of litters). In this way, we offer integrated manufacturing service from Oligonucleotide to finished dosage.

Our capable service is as follows.

- Oligonucleotides manufacture

- Scale up production for Liposome and LNP

Categories
     Drug Delivery Innovations and Strategies
     Oligonucleotide Chemistry, Manufacturing and Controls
Contacts
Shinzo Nakayama, Manager
Phone: +81336653333
Mobile: +819031414657
Fax: +81336653940
Yosuke Sasaki, Product strategy Section, Pharma-Medicals Division, Life & Healthcare Products Department
Phone: +81665352327
Mobile: +819054548911
Fax: +81665352480
Yukihiro Namba, Nagase Medicals Co.,Ltd. Technical Advisor
Phone: +81727815739
Mobile: +818085354697
Fax: +81727819533
Product Showcase
Nucleotide Building Blocks Innovative oligonucleotide synthesis by Building Blocks

Allyl-phosphate blocker is stable and capablel for mass production of oligonucleotides.

Product Brochure
Contract manufacturing service for Liposome, LNP and Micelle formulation Most experienced CMO for liposome and LNP drugs in Japan

Offering CMO service with innovative production method (SQUID) and which is available from lab scale to commercial production.

Product Brochure
Special Events
Oligonucleotides synthesis
Date/Time: any time Location: Please contact me.

We developed novel nucleotide blockers and monomers as new building blocks for manufacturing of oligonucleotide substance. Presented here is its preparation process and applying to oligonucleotide synthesis in liquid and solid phase in use of our building blocks.

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